[I-DOE: Focus Course, 4 days + optional 5th day Advanced DOE]

**I. Statistical Thinking
in Experimental Design**

**A. Framework for Statistical
Thinking and Scientific Method**

**B.
Strategy of Experimentation**

**C.
Simple Comparative Experiments**

**D.
Fundamental Design Concepts
**

**II. Fundamentals
of Analysis: Single Factor Designs**

A. Design Models

B. Completely Randomized Single Factor Designs1. Analysis of Variance (ANOVA)

2. Overall Test of Significant Differences

3. Comparison Among Treatment Means

4. Model Adequacy Checking

5. Non-normal Data: Transformations and Nonparametric Methods

C. Dealing with the Effects of Nuisance Factors1. Blocking Designs

2. Concomitant Variables

**III. Designs for
Process/Product Characterization**

A. Multiple Factors and Factorial Design Structure

B. Screening Designs1. Two Level Designs

2. Fractional Factorial Designs

A. Quantitative Factors and Regression Models

B. Response Surface Designs and Models

___________________________________________

A. Nested Designs and Models (Components of Variance)

B. Factorial Experiments with Random Factors

**VI. Advanced DOE**
(optional 5th day)

A. Expected Mean Squares

B. General Linear Model

C. Mixed Models (Fixed and Random Effects)

D. Nested-Factorial Designs and Mixed Models

E. Constraints on Randomization:Split Plot Designs